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LANGERHANS CELLS
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DeCS
Descriptor
English
:
Langerhans Cells
Descriptor
Spanish
:
Células de Langerhans
Descriptor
Portuguese
:
Células de Langerhans
Tree Number:
A11.066.270.500
A11.436.270.545
A15.382.066.270.500
A15.382.812.260.500
Definition
English
:
Recirculating, dendritic,
antigen-presenting cells
containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the
EPIDERMIS
and are rich in Class II
MAJOR HISTOCOMPATIBILITY COMPLEX
molecules.
Langerhans cells
were the first dendritic cell to be described and have been a model of study for other
dendritic cells
(DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL
DENDRITIC CELLS
.
Indexing Annotation
English
:
cutaneous
cells
: do not confuse with
ISLETS OF LANGERHANS
(pancreas) nor with
GIANT CELLS
, LANGHANS (macrophages)
History Note
English
:
73(69)
Allowable Qualifiers
English
:
chemistry
classification
cytology
drug effects
enzymology
immunology
metabolism
microbiology
pathology
physiology
parasitology
radiography
radiation effects
radionuclide imaging
secretion
transplantation
ultrastructure
ultrasonography
virology
Record Number:
28151
Unique Identifier:
D007801
Occurrence in VHL
:
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